As a fund-raising challenge for the tsunami relief effort, Anders Jacobsen will put his money where my mouth is, so to speak. Works for me. Below is a list of worthwhile groups that could use your support.
International aid organizations:
UNICEF (United Nations Children's Fund)
Disasters Emergency Comittee (DEC) - comprises a raft of aid agencies, including the below and others
And feel free to leave a comment with Anders Jacobsen, who posted Webloggers: Give to tsunami victims and I'll give too! It will be interesting to see what sort of response this generates.
Hat Tip to Jeff Jarvis.